COVID-19 pathophysiology: A review (DOI: 10.1016/j.clim.2020.108427)

Publication Metadata

DOI	10.1016/j.clim.2020.108427
PubMedID	32325252
PMCID	PMC7169933
PubTator	https://www.ncbi.nlm.nih.gov/research/pubtator/?view=docsum&query=PMC7169933
Sections in this Publication
Section	Section 1: Introduction (from DOI: 10.1016/j.clim.2020.108427)
Section	Section 2: Epidemiological data of COVID-19 (from DOI: 10.1016/j.clim.2020.108427)
Section	Section 3: Mechanism of SARS-CoV-2 invasion into host cells (from DOI: 10.1016/j.clim.2020.108427)
Section	Section 4: Host response to SARS-CoV-2 (from DOI: 10.1016/j.clim.2020.108427)
Section	Section 5: Potential explanation for the difference between children and adults in COVID-19 (from DOI: 10.1016/j.clim.2020.108427)
Section	Section 6: Conclusions (from DOI: 10.1016/j.clim.2020.108427)
Section	Financial support (from DOI: 10.1016/j.clim.2020.108427)
Section	Declaration of Competing Interest (from DOI: 10.1016/j.clim.2020.108427)
Section	References (from DOI: 10.1016/j.clim.2020.108427)
Author(s) [max 10]
1st	Yuki K (1st author of DOI: 10.1016/j.clim.2020.108427)
2nd	Fujiogi M (2nd author of DOI: 10.1016/j.clim.2020.108427)
3rd	Koutsogiannaki S (3rd author of DOI: 10.1016/j.clim.2020.108427)
Dataset	Pubtator Central BioC-JSON formatted article files

Research article published in:
Clin. Immunol.; 2020 Apr 20 108427. DOI: http://doi.org/10.1016/j.clim.2020.108427

Abstract

In December 2019, a novel coronavirus, now named as SARS-CoV-2, caused a series of acute atypical respiratory diseases in Wuhan, Hubei Province, China. The disease caused by this virus was termed COVID-19. The virus is transmittable between humans and has caused pandemic worldwide. The number of death tolls continues to rise and a large number of countries have been forced to do social distancing and lockdown. Lack of targeted therapy continues to be a problem. Epidemiological studies showed that elder patients were more susceptible to severe diseases, while children tend to have milder symptoms. Here we reviewed the current knowledge about this disease and considered the potential explanation of the different symptomatology between children and adults.

License

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.