Introduction section from DOI: 10.3390/pathogens9020148
Introduction
| Article | Emergence of Novel Coronavirus 2019-nCoV: Need for Rapid Vaccine and Biologics Development (DOI: 10.3390/pathogens9020148) |
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The global health system consists of a network of organizations, including many private and public health sectors operating at different regional or global levels that have developed a stringent system that can provide effective protection to humans against emerging and re-emerging diseases. Though mortality associated with various infectious diseases have reduced in recent years and global life expectancy has increased in many parts of the world, infectious disease threats still remain one of the major global challenges and concerns even now [1] . The global health system is often confronted by emerging pathogens responsible for expanding an array of infectious diseases such as Zika, Chikungunya, Ebola, Nipah, Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and Influenza. The emergence of the 2019 novel coronavirus (2019-nCoV) has recently added to the list of problematic emerging pathogens in the 21st century, which was suspected to originate from the persons exposed to a seafood or wet market in Wuhan, Hubei Province, China, suggesting animal-to-human transmission [2, 3] . This virus strain is previously unknown and was reported to infect humans for the first time. The virus continues to expand rapidly throughout the world. Many confirmed and susceptible cases have been identified in Wuhan, China, and exported cases have also been reported in neighboring countries including Thailand, Japan, Korea, Taiwan, and other countries including the United States, Canada, and European countries, which proves that the virus has the potential for quick dissemination across borders. In response to the rapid spread of the virus, many countries have tightened their border security, investigating people showing symptoms, and have taken necessary emergency steps to control its spread. Due to the increasing number of cases in China and other countries, the WHO has declared the 2019-nCoV outbreak a global health emergency of international concern on 30 January 2020 [4].
