Can the Coronavirus Disease 2019 (COVID-19) Affect the Eyes? A Review of Coronaviruses and Ocular Implications in Humans and Animals (DOI: 10.1080/09273948.2020.1738501)
| Keywords | Coronavirus, COVID-19, novel coronavirus, severe acute respiratory syndrome coronavirus-2 |
|---|---|
| DOI | 10.1080/09273948.2020.1738501 |
| PMCID | PMC7103678 |
| Sections in this Publication | |
| Section | Introduction (Section from DOI: 10.1080/09273948.2020.1738501) |
| Section | The Coronavirus Structure and Host (Section from DOI: 10.1080/09273948.2020.1738501) |
| Section | Human Coronaviruses and the Evidence for Ocular Manifestations (Section from DOI: 10.1080/09273948.2020.1738501) |
| Section | Feline Coronaviruses and Ocular Manifestations (Section from DOI: 10.1080/09273948.2020.1738501) |
| Section | Mouse Coronaviruses and Ocular Implications (Section from DOI: 10.1080/09273948.2020.1738501) |
| Section | Conclusion (Section from DOI: 10.1080/09273948.2020.1738501) |
| Author(s) [max 10] | |
| 1st | Ivan Seah (1st author of DOI 10.1080/09273948.2020.1738501) |
| 2nd | Rupesh Agrawal (2nd author of DOI 10.1080/09273948.2020.1738501) |
| Dataset | COVID-19 Open Research Dataset (CORD-19). 2020. Version 2020-03-20. |
Published in:
Ocular Immunology and Inflammation (2020) Taylor & Francis
http://doi.org/10.1080/09273948.2020.1738501
ABSTRACT
In December 2019, a novel coronavirus (CoV) epidemic, caused by the severe acute respiratory syndrome coronavirus – 2 (SARS-CoV-2) emerged from China. This virus causes the coronavirus disease 2019 (COVID-19). Since then, there have been anecdotal reports of ocular infection. The ocular implications of human CoV infections have not been widely studied. However, CoVs have been known to cause various ocular infections in animals. Clinical entities such as conjunctivitis, anterior uveitis, retinitis, and optic neuritis have been documented in feline and murine models. In this article, the current evidence suggesting possible human CoV infection of ocular tissue is reviewed. The review article will also highlight animal CoVs and their associated ocular infections. We hope that this article will serve as a start for further research into the ocular implications of human CoV infections.
