SARS-CoV-2: Is it the newest spark in the TORCH? (DOI: 10.1016/j.jcv.2020.104372)

Publication Metadata

Keywords	Congenital infection, TORCH infection, SARS-CoV-2 vaccines, COVID-19, SARS-CoV-2
DOI	10.1016/j.jcv.2020.104372
PubMedID	32335336
PMCID	PMC7195345
PubTator	https://www.ncbi.nlm.nih.gov/research/pubtator/?view=docsum&query=PMC7195345
Sections in this Publication
Section	Section 1: Introduction (from DOI: 10.1016/j.jcv.2020.104372)
Section	Section 2: Is SARS-CoV-2 a congenital or perinatally-acquired pathogen for the neonate? (from DOI: 10.1016/j.jcv.2020.104372)
Section	Section 2.1: Lessons from animal models (from DOI: 10.1016/j.jcv.2020.104372)
Section	Section 2.2: Congenital and perinatal infections with coronaviruses other than SARS-CoV-2 (from DOI: 10.1016/j.jcv.2020.104372)
Section	Section 2.3: Congenital and perinatal infections with SARS-CoV-2 (from DOI: 10.1016/j.jcv.2020.104372)
Section	Section 3: Conclusions and priorities for future research (from DOI: 10.1016/j.jcv.2020.104372)
Section	Funding (from DOI: 10.1016/j.jcv.2020.104372)
Section	Declaration of Competing Interest (from DOI: 10.1016/j.jcv.2020.104372)
Section	References (from DOI: 10.1016/j.jcv.2020.104372)
Author(s) [max 10]
1st	Muldoon KM (1st author of DOI: 10.1016/j.jcv.2020.104372)
2nd	Fowler KB (2nd author of DOI: 10.1016/j.jcv.2020.104372)
3rd	Pesch MH (3rd author of DOI: 10.1016/j.jcv.2020.104372)
4th	Schleiss MR (4th author of DOI: 10.1016/j.jcv.2020.104372)
Dataset	Pubtator Central BioC-JSON formatted article files

Research article published in:
J. Clin. Virol.; 2020 Apr 14 ; 127 104372 DOI: http://doi.org/10.1016/j.jcv.2020.104372

Abstract

Amid the rapidly evolving global coronavirus disease 2019 (COVID-19) pandemic that has already had profound effects on public health and medical infrastructure globally, many questions remain about its impact on child health. The unique needs of neonates and children, and their role in the spread of the virus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) should be included in preparedness and response plans. Fetuses and newborn infants may be uniquely vulnerable to the damaging consequences of congenitally- or perinatally-acquired SARS-CoV-2 infection, but data are limited about outcomes of COVID-19 disease during pregnancy. Therefore, information on illnesses associated with other highly pathogenic coronaviruses (i.e., severe acute respiratory syndrome (SARS) and the Middle East respiratory syndrome [MERS]), as well as comparisons to common congenital infections, such as cytomegalovirus (CMV), are warranted. Research regarding the potential routes of acquisition of SARS-CoV-2 infection in the prenatal and perinatal setting is of a high public health priority. Vaccines targeting women of reproductive age, and in particular pregnant patients, should be evaluated in clinical trials and should include the endpoints of neonatal infection and disease.

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